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Furthermore, there are no adverse effects on the skin by the BP (140)

The injection of CagA leads to aberrant cellular signaling, including interactions with Src homology 2 (SH2) domain-containing protein tyrosine phosphatase 2 (SHP2) and phosphoinositide 3-kinase (PI3K), driving the transformation of normal epithelial cells into neoplastic ones (173)

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Klahr, S

CD4 /CD8 progenitor T cells do not display the UPR but greatly increase it during maturation as CD4 + /CD8 + T cells